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RIO DE JANEIRO， Aug. 3 (Xinhua) -- The International Olympic Committee Wednesday approved five new sports for the 2020 Tokyo Olympic Games， including baseball and softball， karate， skateboard， sports climbing and surfing.
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by Christian Edwards
SYDNEY nike air max 97 scontate , April 24 (Xinhua) -- In a remarkable breakthrough for global gene science, researchers at the Australian University of New South Wales (UNSW) have for the first time delivered regenerative gene therapy, successfully re-growing auditory nerves - effectively recreating tonal sounds for the deaf.
By employing electrical pulses delivered from a cochlear implant through auditory senses, the breakthrough brings hope to millions of people around the world that previously could not detect the tones that deliver music or other more complex sounds.
The research, published Thursday in the prestigious journal Science Translational Medicine also heralds a possible new way of treating a range of neurological disorders, including Parkinson's disease nike air max 2017 scontate , and psychiatric conditions such as depression through this novel way of delivering gene therapy.
"People with cochlear implants do well with understanding speech, but their perception of pitch can be poor, so they often miss out on the joy of music," says UNSW Professor Gary Housley, senior author of the research paper.
"Ultimately, we hope that after further research nike air max 2018 elite donne scontate , people who depend on cochlear implant devices will be able to enjoy a broader dynamic and tonal range of sound, which is particularly important for our sense of the auditory world around us and for music appreciation," said Professor Housley, who is also the Director of the Translational Neuroscience Facility at UNSW Medicine.
The research, supported by Cochlear Limited through an Australian Research Council Linkage Project grant, has been five years in development.
The work centers on regenerating surviving nerves after age- related or environmental hearing loss nike air max 2018 elite uomo scontate , using existing cochlear technology. The cochlear implants are "surprisingly efficient" at localized gene therapy in the animal model, when a few electric pulses are administered during the implant procedure.
"This research breakthrough is important because while we have had very good outcomes with our cochlear implants so far, if we can get the nerves to grow close to the electrodes and improve the connections between them, then we'll be able to have even better outcomes in the future," says Jim Patrick, Chief Scientist and Senior Vice-President nike air max 2018 elite scontate , Cochlear Limited.
It has long been established that the auditory nerve endings regenerate if neurotrophins a naturally occurring family of proteins crucial for the development, function and survival of neurons are delivered to the auditory portion of the inner ear, the cochlea.
But until now, research has stalled because safe, localized delivery of the neurotrophins can't be achieved using drug delivery, nor by viral-based gene therapy.
Professor Housley and his team at UNSW developed a way of using electrical pulses delivered from the cochlear implant to deliver the DNA to the cells close to the array of implanted electrodes. These cells then produce neurotrophins.
"No-one had tried to use the cochlear implant itself for gene therapy www.airmax2018scontate.it ," says Professor Housley. "With our technique, the cochlear implant can be very effective for this."
While the neurotrophin production dropped away after a couple of months, Professor Housley says ultimately the changes in the hearing nerve may be maintained by the ongoing neural activity generated by the cochlear implant.
"We think it's possible that in the future this gene delivery would only add a few minutes to the implant procedure," says the paper's first author, Jeremy Pinyon, whose PhD is based on this work. "The surgeon who installs the device would inject the DNA solution into the cochlea and then fire electrical impulses to trigger the DNA transfer once the implant is inserted."
Integration of this technology into other "bionic" devices such as electrode arrays used in deep brain stimulation (for the treatment of Parkinson's disease and depression scarpe nike air max 2018 scontate , for example) could also afford opportunities for safe, directed gene therapy of complex neurological disorders.
"Our work has implications far beyond hearing disorders," says co-author Associate Professor Matthias Klugmann, from the UNSW Translational Neuroscience Facility research team. "Gene therapy has been suggested as a treatment concept even for devastating neurological conditions and our technology provides a novel platform for safe and efficient gene transfer into tissues as delicate as the brain."
Hong Kong's chief executive Leung Chun-Ying will visit Hainan on Friday and Saturday to attend the Boao Forum for Asia Annual Conference 2015, the Hong Kong Special Administrative Region Government's news website said Wednesday.[Special coverage]
Leung will attend a discussion session on Friday as one of the panelists, on opportunities for multinationals and the role of Hong Kong in "One Belt and One Road".
On Friday evening nike air max 2018 uomo scontate , he will attend the "Global Economic Outlook 2015: A Dialogue with BFA Board of Directors" dinner reception, and meet student volunteers from Hong Kong.
Leung will attend the opening plenary of the annual conference on Saturday morning, and return to Hong Kong in the afternoon.
KIGALI, Aug. 8 (Xinhua) -- Kenyan nationals residing in Rwanda on Tuesday participated in general elections by casting their votes at the diplomatic mission in the capital city Kigali.
The elections in Kenya are for the President, county governor, senator nike air max 2018 scontate , Member of Parliament, woman representative and member of county assembly.
The voters began arriving at the Kenyan High Commission in Kacyiru sector, Gasabo district as early as 6 a.m. where a polling station had. Wholesale Soccer Shirts Cheap NHL Hoodies Free Shipping Cheap NBA Hoodies Free Shipping Wholesale Jerseys Wholesale Shirts Wholesale Shirts Wholesale Hoodies Wholesale Hats Wholesale NHL Jerseys Wholesale NCAA Jerseys |
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